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Fort Peck Nutritional Epigenetics Project

Collaborating With Food Ingredient and Health Research Institute Means Supporting Your Community

At the Fort Peck Indian Reservation, we collaborated with the community college and food research institutes to develop an online nutritional epigenetics course as an intervention for a clinical trial. The curriculum we created was culturally competent to meet the needs of American Indian students. The goals of the intervention study were to determine the impact of dietary inorganic mercury exposure on glucose homeostasis and reduce risk factors for the development of Type-2 Diabetes. Our aim was to improve student diet and health outcomes.

Ford peak nutritional collage

Study Design With Biomarker Collection

Biomarker Collection

Biomarker Collection

In addition to collecting pre-post intervention diet survey data, we measured pre-post intervention BMI, weight, fasting glucose, insulin, and inorganic mercury levels, which are crucial metrics often analyzed by food research institutes.

Study Results

Dietary Changes

Students who completed the online nutritional epigenetics course significantly improved their diets (p<0.01). They significantly decreased their intake of ultra-processed foods (p<0.01) and significantly increased their intake of whole, unprocessed foods (p<0.01).

Biomarker Changes

Students who took the online nutritional epigenetics course showed significant reductions in their fasting blood glucose levels (p<0.01) and lower levels of inorganic mercury in their blood (p=0.05) compared to the students who did not take the online course.

Student Learning

Students who took the online nutritional epigenetics course were required to develop an educational tool to share what they learned with friends and family as part of a final project. Some students developed informative brochures while others gave PPT presentations.

Major Finding

Blood inorganic mercury is directly associated with glucose levels in the human population!

At the Fort Peck Indian Reservation, we collaborated with the community college and food research institutes to develop an online nutritional epigenetics course as an intervention for a clinical trial. The curriculum we created was culturally competent to meet the needs of American Indian students. The goals of the intervention study were to determine the impact of dietary inorganic mercury exposure on glucose homeostasis and reduce risk factors for the development of Type-2 Diabetes. Our aim was to improve student diet and health outcomes.

NHANES data analysis reveals I-Hg exposure linked to Type 2 Diabetes in 16,232 participants.

We presented our findings at the Smithsonian Institute.

Check out this great video at the National Museum of the American Indian, which also highlights the work of food research institutes!

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